The U.S. Agency for Toxic Substances and Disease Registry tasked with protecting Americans from health threats is facing growing pressure to perform a nationwide health study on perfluorinated compounds — unregulated chemicals being found in drinking water supplies across the country, including locally. More:

• Pressure growing on feds to do PFC health study–Bucks County Courrier Times
• Letter to the US Center for Disease Control and Prevention requesting to launch a health study in communities affected by PFAS
• CDC: Some in Horsham, Warrington, Warminster exposed to PFCs several times the safe level–The Intelligencer

Combined exposures to polybrominated diphenyl ethers (PBDEs) may exceed acceptable levels in breastfeeding infants and in small children even for moderate (vs. high) exposure scenarios, according to a study. The study also suggests that acceptable levels of combined PBDEs may be exceeded in adults whose diets are high in fish and corroborates reports from several epidemiological studies of associations between PBDE exposures and neurobehavioral outcomes. More:

• A Human Mixture Risk Assessment for Neurodevelopmental Toxicity Associated with Polybrominated Diphenyl Ethers Used as Flame Retardants (Research article)

Increased exposure among pregnant women to a class of flame-retardant chemicals found in older furniture and other everyday consumer products is linked to lower IQs in their children. Examining data from nearly 3,000 mother-child pairs from previous studies done around the world, researchers concluded that every tenfold increase in women’s exposure during pregnancy to chemicals known as polybrominated diphenyl ethers, or PBDEs, was associated with a 3.7-point decrease in their children’s IQ. More:

• Flame retardants linked to lower child IQ–SFgate
• Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis (Research article)

Many of the products we use every day contain chemicals of concern that may be harming our health. Many of these substances can be grouped into “Six Classes”, each containing similar chemicals. The Six Classes approach allows us to better understand these chemicals, their functions, where they are used, and how they can be avoided. It can prevent a cycle of “regrettable substitution,” whereby a phased out harmful chemical is replaced with a closely related chemical which may cause similar harm. More:

• The Six Classes Approach to Reducing Chemical Harm–The Green Science Policy Institute
• Stop playing whack-a-mole with hazardous chemicals–The Washington Post
• How to Save Your Sperm–The New York Times

FOUNTAIN — Water providers and residents south of Colorado Springs chafed as the U.S. Air Force on Tuesday unveiled a nine-month study verifying that firefighting foam used at Peterson Air Force Base contaminated water and soil with toxic perfluorinated chemicals at levels more than 1,000 times higher than a national health advisory limit. More:

• Air Force admits firefighting foam that was spilled on base contaminated water and soil; people south of Colorado Springs left in lurch–The Denver Post
• Water tainted with perfluorocarbons by U.S. military is focus of legislation–Chemical & Engineering News
• Nearly 400 military bases must be tested for drinking water contamination — and it will take years–The Philadelphia Inquirer

Making the chemical used in many nonstick frying pans, stain-resistant carpets and fire-fighting foams can pollute drinking water. Known as PFOA, this chemical can persist unchanged in the environment for years — perhaps for centuries or longer. And that can be troubling because studies have suggested that PFOA can harm the health of people and animals. But a new lab-made chemical can now remove PFOA from water. More:

• New ‘magnet’ pulls pesky nonstick pollutants from drinking water–Science News for Students
• β-Cyclodextrin Polymer Network Sequesters Perfluorooctanoic Acid at Environmentally Relevant Concentrations (Research article)

The EPA encouraged companies beginning in 2006 to phase out PFOA and related chemicals. The industry replaced them with GenX (perfluoro-2-propoxypropanoic acid) and other new-generation agents known as perfluorinated compounds, or PFAS. According to the industry, the new class is eliminated faster from the body, making them safer. However, several scientists have expressed concerns, citing their persistence in the environment including plant life, as well as a dearth of studies. More:

• On U.S. Rivers, Teflon’s Old Cancer Ties Are Stoking New Fears–Bloomberg
• Wilmington residents, NC officials seek answers in toxic tap water meeting–WRAL.com
• Formula-fed infants at highest risk for GenX health effects–WECT.com
• Joint DEQ, DHHS Release: State Releases First Water Quality Data, Updated Health Information for GenX in Cape Fear River–North Caroline Department of Health and Human Services and Department of Environmental Quality (NC DHHS, DEQ)
• Questions and Answers Regarding North Carolina Department of Health and Human Services UpdatedRisk Assessment for GenX (Perfluoro-2-propoxypropanoic acid) (NC DHHS)

Fish are a source of persistent organic pollutants (POPs) in the human diet. Although species, trophic level, and means of production are typically considered in predicting fish pollutant load, and thus recommendations of consumption, capture location is usually not accounted for. Capture location is an important consideration when assessing the level and risk of human exposure to POPs through ingestion of wild fish. More:

• Geographic Differences in Persistent Organic Pollutant Levels of Yellowfin Tuna (Research article)

In a warming world new opportunities open up for disease-bearing mosquitoes, spreading Ethiopia’s malaria zone to higher altitudes. For the malaria parasite, things are looking up. As climates change, and mountain regions warm, conditions become favourable not just for the parasite but for the mosquito that carries it. New research suggests that Ethiopia’s malaria zone could soon include the highlands, for centuries free of the disease’s ravages. More:

• High-flying insects expand Ethiopia’s malaria zone–Climate News Network
• Temperature suitability for malaria climbing the Ethiopian Highlands (Research article)

The known extent of the contamination of U.S. communities with PFCs – highly fluorinated toxic chemicals, also known as PFASs,[*] that have been linked to cancer, thyroid disease, weakened immunity and other health problems – continues to expand with no end in sight. New research from EWG and Northeastern University in Boston details PFC pollution in tap water supplies for 15 million Americans in 27 states and from more than four dozen industrial and military sources from Maine to California. More:

• Mapping a contamination crisis - PFCs Pollute Tap Water–Environmental Working Group
• Toxic fluorinated chemicals in tap water and at industrial or military sites in the USA (Interactive map)

A study of the toxic perfluorinated chemicals found in water near U.S. military airports has measured drinking-water contamination at an undisclosed site at levels more than 100 times higher than a federal health advisory limit. Colorado School of Mines researchers also found that the carbon filters being installed by hard-hit communities — including Fountain and Widefield, south of Peterson Air Force Base — fail to fully remove the chemicals. More:

• Toxic firefighting chemicals can’t be removed from water using standard filters, Mines research shows–The Denver Post
• Mines researchers find newly discovered fluorinated chemicals more difficult to filter from water–Colorado School of Mines
• Sorption of Poly- and Perfluoroalkyl Substances (PFASs) Relevant to Aqueous Film-Forming Foam (AFFF)-Impacted Groundwater by Biochars and Activated Carbon (Research article)
• Perfluorinated chemicals taint drinking water Linked to health problems, PFOA and PFOS leave a legacy that EPA is just starting to address–C&EN

Some chemicals can mimic hormones, and in doing so wrongly turn on or off important bodily processes. Hormones are like the managers of the body’s organs and other tissues. These chemicals order cells to switch on or off some particular activity. Sometimes industrial chemicals and pollutants can mimic these managers. When such imposters enter the body, they can alter when or how an organism develops, what it looks like — even whether it gets some disease. More:

• Explainer: What are endocrine disruptors?–Science News for Students

A research team at the University of California San Diego (UCSD) discovered that a common marine sponge hosts bacteria that produce toxic compounds that are nearly identical to man-made flame retardants. More:

• Bacteria in marine sponges produce flame retardant-like compounds–Environmental Factor
• Study Finds Bacteria Living in Marine Sponge Produce Toxic Flame Retardant-Like Compounds–Scripps Institutions of Oceanography
• Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges (Research article)
• How sea sponges make toxic flame retardants–The San Diego Union Tribune

Last year, one of Britain’s last surviving killer whales was found dead on the shores of a Scottish island. The whale, known as Lulu, had died after becoming entangled in fishing lines, but subsequent tests revealed that her body contained one of the highest levels ever recorded of polychlorinated biphenyls (PCB), a toxic chemical that many countries have banned since the 1970s. More:

• Tackling a toxic legacy – UN environment
• Consolidated assessment of efforts made toward the elimination of polychlorinated biphenyls (UNEP report)

Our modern lives are drenched in chemicals, some of which can mimic hormones in our body's endocrine system. Obesity, type 2 diabetes, and some cancer rates are on the rise in humans, while sperm count and fertility are on a downward slide in some populations. What if chemical exposure was partly responsible for these trends?. More:

• Endocrine disrupting chemicals: Is your home making you sick? – ABC News Australia

Forty years ago, feline hyperthyroidism was virtually nonexistent. Now it’s an epidemic — and some scientists think a class of everyday chemicals might be to blame. More:

• The Mystery of theWasting House-Cats–The New York Times
• PBDE levels in cats may be associated to Feline Hyperthyroidism–MiSSE
• Higher PBDE Serum Concentrations May Be Associated with Feline Hyperthyroidism in Swedish Cats (Research article)

The animal, called Lulu, was found dead on the Isle of Tiree in Scotland last year after becoming entangled in fishing lines. But tests now reveal her body contained among the highest levels of polychlorinated biphenyls, or PCBs, ever recorded. The levels of PCB contamination in Lulu were incredibly high, surprisingly so. They were 20 times higher than the safe level that we would expect for cetaceans to be able to manage. More:

• 'Shocking' levels of PCB chemicals in UK killer whale Lulu–BBC
• UK killer whale died with extreme levels of toxic pollutants–The Guardian
• Race is on to rid UK waters of PCBs after toxic pollutants found in killer whale–The Guardian
• Learn about Polychlorinated Biphenyls (PCBs)–US EPA

When you plunk an adult zebrafish into an unfamiliar tank, it will behave predictably: the small, striped, freshwater minnow freezes for up to a minute, slowly begins to explore the tank, and then, when it’s good and ready, swims around as if it’s been there the whole time. Yet adult zebrafish that were born in water contaminated by a common class of toxicants—polychlorinated biphenyls, or PCBs—have a much more hesitant reaction. More:

• Toxicant-Triggered Anxiety: Juvenile fish exposed to a common environmental toxicant show signs of anxiety–Hakai Magazine
• Delayed effects of developmental exposure to low levels of the aryl hydrocarbon receptor agonist 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) on adult zebrafish behavior (Research article)
• Polychlorinated Biphenyls (PCBs) Toxicity–What Are Adverse Health Effects of PCB Exposure?–US Agency for Toxic Substances and Disease Registry

A new global survey finds that recycling plastics containing toxic flame retardant chemicals found in electronic waste results in contamination of the world’s best-selling toy along with other children’s products. More:

• Recycling Contaminates Plastic Children’s Toys with Toxic Chemicals from Electronic Waste–IPEN
• POPs Recycling Contaminates Children's Toys with Toxic Flame Retardants (Report)
• Recycling contaminates children’s toys with toxic chemicals from electronic waste – Vanguard Nigeria

Certain man-made chemicals -- believed to be in the bloodstream of nearly every person on Earth thanks to heavy use in consumer manufactured products -- also build up in the brains, hearts, livers, bones and skin of mice according to a study published last week by researchers at the UAB School of Medicine and the University of Notre Dame. More:

• Cancer-linked chemicals build up in 'every organ' in mice, UAB researchers find–AL.com (Alabama)
• Radiosynthesis and Biological Distribution of 18F-Labeled Perfluorinated Alkyl Substances (Research letter)